Currently, the wording of the indication in section 4.1 of the SmPC (Summary of Product Characteristics) for recently approved centrally authorised medicinal products intended for the treatment of patients with type 2 diabetes contains 2 sections addressing mono- and combination therapy,[…] One of the reasons to specifically describe monotherapy in the indication wording is to reflect the widely accepted recommendation to use metformin as first line treatment.

 

Posted on the EMA website on 3 March 2014