Hydroxyzine (Atarax, Ucerax): risk of QT interval prolongation and Torsade de Pointes

The maximum adult daily dose of hydroxyzine is now 100 mg.


Codeine for cough and cold: restricted use in children

Do not use codeine in children under 12 as it is associated with a risk of respiratory side effects.


High strength, fixed combination and biosimilar insulin products: minimising the risk of medication error

Several new high strength insulin products are now on the market.


Letters sent to healthcare professionals in March 2015

Last month, letters were sent regarding ketoconazole HRA and radium-223 dichloride (Xofigo).



Posted on the UK MHRA website on 29 April 2015