Simeprevir with sofosbuvir: risk of severe bradycardia and heart block when taken with amiodarone
Avoid concomitant use of amiodarone with simeprevir (Olysio▼) and sofosbuvir (Sovaldi▼) combination therapy, unless other antiarrhythmics cannot be given.
Letters sent to healthcare professionals in July 2015
Last month, letters were sent regarding SGLT2 inhibitors and Xgeva▼ (denosumab).