Ibrutinib (Imbruvica▼): reports of ventricular tachyarrhythmia; risk of hepatitis B reactivation and of opportunistic infections
Temporarily discontinue ibrutinib in patients who develop symptoms suggestive of ventricular arrhythmia and assess benefit-risk before restarting therapy.
Corticosteroids: rare risk of central serous chorioretinopathy with local as well as systemic administration
Central serous chorioretinopathy is a retinal disorder that has been linked to the systemic use of corticosteroids.
It is recommended that 2 adrenaline auto-injectors are prescribed, which patients should carry at all times.
Letters were sent about ibrutinib, daclizumab, aflibercept, valproate medicines, and arsenic trioxide.
An alert was recently issued about Prismaflex haemofiltration machines.