Ibrutinib (Imbruvica▼): reports of ventricular tachyarrhythmia; risk of hepatitis B reactivation and of opportunistic infections

Temporarily discontinue ibrutinib in patients who develop symptoms suggestive of ventricular arrhythmia and assess benefit-risk before restarting therapy.

Corticosteroids: rare risk of central serous chorioretinopathy with local as well as systemic administration

Central serous chorioretinopathy is a retinal disorder that has been linked to the systemic use of corticosteroids.

Adrenaline auto-injectors: updated advice after European review

It is recommended that 2 adrenaline auto-injectors are prescribed, which patients should carry at all times.

Letters sent to healthcare professionals in July 2017

Letters were sent about ibrutinib, daclizumab, aflibercept, valproate medicines, and arsenic trioxide.

Medical Device Alerts issued in July 2017

An alert was recently issued about Prismaflex haemofiltration machines.

Posted on the UK MHRA website on 15 August 2017