Letters sent to healthcare professionals in May 2016
In May 2016, letters were sent regarding Nexplanon (etonogestrel implant) and ERWINASE.
Topical miconazole, including oral gel: reminder of potential for serious interactions with warfarin
In view of reports of serious bleeding events in patients taking miconazole and warfarin, we are considering further measures to minimise the risk of potentially serious interactions between miconazole and warfarin.
Nexplanon (etonogestrel) contraceptive implants: reports of device in vasculature and lung
There have been rare reports of Nexplanon implants having reached the lung via the pulmonary artery.
A signal of increased lower limb amputation (primarily of the toe) in people taking canagliflozin compared with placebo in a clinical trial in high cardiovascular risk patients is currently under investigation.