SGLT2 inhibitors: updated advice on increased risk of lower-limb amputation (mainly toes)

Canagliflozin may increase the risk of lower-limb amputation (mainly toes) in patients with type 2 diabetes.

Launch of pilot reporting scheme for harms associated with illicit drugs, particularly new psychoactive substances

We are launching a pilot scheme for healthcare professionals in the UK to report suspected adverse reactions to illicit drugs, particularly new psychoactive substances.

Posted on the UK MHRA website 22 March 2017